Novel Lab Research: “CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice”

Wang, CH, Lundh M, Fu A, Kriszt R, Huang TL, Lynes MD, Leiria LO, Shamsi F, Darcy J, Greenwood BP, Narain NR, Tolstikov V, Smith KL, Emanuelli B, Chang YT, Hagen S, Danial NN, Kiebish MA, Tseng YH. CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice. Sci Transl Med 2020;12(558):1-14. PMID: 32848096. DOI: 10.1126/scitranslmed.aaz8664.

https://www.joslin.org/about/news-media/transplanted-brown-fat-cells-hold-promise-obesity-and-diabetes

https://www.wbur.org/commonhealth/2020/08/27/crispr-white-fat-brown-fat

https://gizmodo.com/researchers-give-mice-super-calorie-burning-fat-cells-u-1844859172

https://crisprmedicinenews.com/news/crispr-gene-therapy-make-fat-cells-burn-fat-and-prevent-obesity-in-mice/

https://medicalxpress.com/news/2020-08-transplanted-brown-fat-like-cells-obesity-diabetes.html

https://www.inverse.com/mind-body/crispr-cell-therapy-brown-fat-white-fat-obesity

https://www.newscientist.com/article/2252925-body-fat-transformed-by-crispr-gene-editing-helps-mice-keep-weight-off/

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