https://www.nih.gov/news-events/nih-research-matters/uncovering-origins-brown-fat
Researchers identified previously unknown origins of brown fat, which burns energy to create heat for the body.
Novel Lab Research: “CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice”
Wang, CH, Lundh M, Fu A, Kriszt R, Huang TL, Lynes MD, Leiria LO, Shamsi F, Darcy J, Greenwood BP, Narain NR, Tolstikov V, Smith KL, Emanuelli B, Chang YT, Hagen S, Danial NN, Kiebish MA, Tseng YH. CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice. Sci Transl Med 2020;12(558):1-14. PMID: 32848096. DOI: 10.1126/scitranslmed.aaz8664.
https://www.wbur.org/commonhealth/2020/08/27/crispr-white-fat-brown-fat
https://gizmodo.com/researchers-give-mice-super-calorie-burning-fat-cells-u-1844859172
https://medicalxpress.com/news/2020-08-transplanted-brown-fat-like-cells-obesity-diabetes.html
https://www.inverse.com/mind-body/crispr-cell-therapy-brown-fat-white-fat-obesity
“Integrated metabolomics reveals altered lipid metabolism in adipose tissue in a model of extreme longevity,” published in GeroScience (2020).
Authors: Justin Darcy, Yimin Fang, Samuel McFadden, Matthew D. Lynes, Luiz O. Leiria, Jonathan M. Dreyfuss, Valerie Bussburg, Vladimir Tolstikov, Bennett Greenwood, Niven R. Narain, Michael A. Kiebish, Andrzej Bartke & Yu-Hua Tseng
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